Composition : Sparfloxacin INN 200 mg.
Indications : Exacerbations of chronic bronchitis, community acquired pneumonia, sinusitis, urinary tract infections, gonococcal urethritis and non-gonococcal urethritis, chancroid and other sexually transmitted diseases. Skin and soft tissue infections. Leprosy and other infections.
Dosage & Administration : Patients with normal renal function 2 tablets (400 mg) on the first day as a loading dose. Followed by 1 tablet (200 mg) daily for a total 10 days of therapy. For urinary tract infections 1 tablet (200 mg) loading dose followed by ½ tablet (100 mg) daily is generally recommended. In gonococcal urethritis 1 tablet (200 mg) as a single dose is recommended.
Patients with renal impairment (creatinine clearance <30 ml/min) is 2 tablets (400 mg) taken on the first day as a loading dose. Thereafter, 1 tablet (200 mg) should be taken every 48 hours for a total of 9 days of therapy.