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Home  /  منتجاتنا  /  Pharmaceuticals  /  Limbix Amitriptyline USP & Chlordiazepoxide USP

Limbix Amitriptyline USP & Chlordiazepoxide USP

Supply: Each box contains 5 X 10 tablets in blister pack.

Description: LIMBIX combines Amitriptyline, a tricyclic antidepressant and Chlordiazepoxide, an anxiolytic. Amitriptyline inhibits the reuptake of norepinephrine and serotonin in brain. This interference with the reuptake is responsible for antidepressant activity of Amitriptyline. Chlordiazepoxide works by enhancing GABA-mediated chloride influx through GABA receptor channels, causing membrane hyperpolarization. The net neuro-inhibitory effects result in the observed sedative and anxiolytic effect.

Composition: Each tablet contains Amitriptyline Hydrochloride USP 14.15 mg (equivalent to 12.5 mg Amitriptyline) + Chlordiazepoxide USP 5 mg.  

Indication: LIMBIX is indicated for the treatment of patients with moderate to severe depression associated with moderate to severe anxiety. Symptoms likely to respond in the first week of treatment include: insomnia, feelings of guilt or worthlessness, agitation, psychic and somatic anxiety, suicidal ideation and anorexia.

Dosage & Administration: Optimum dosage varies with the severity of the symptoms and the response of the individual patient. When a satisfactory response is obtained, dosage should be reduced to the smallest amount needed to maintain the remission. The larger portion of the total daily dose may be taken at bedtime. In some patients, a single dose at bedtime may be sufficient.

LIMBIX Tablets in an initial dosage of 3 or 4 tablets daily in divided doses is satisfactory.

 OR AS DIRECTED BY THE PHYSICIAN.

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